The Game has new issues with the whole Dr. Dre crew.

As such, Wack 100 says Game has his sites on Eminem specifically.

In a new chat, Wack said Game will be coming after Shady on Game's new album.

"This n*gga gonna start another fire. We starting a fire.  The Black Slimy Shady.  It's coming.  That n*gga better be ready.  Cause this n*gga went crazy," Wack explained.

"Coming for Eminem?" he was asked.

"He coming like a motherf*cker.  You responded to Machine Gun Kelly and Nick Cannon," Wack said. "That n*gga Em is a disrespectful n*gga ... That n*gga better be ready ... Game gonna write 200 bars on him."

And what if 50 Cent gets involved?

"50 gonna sit his old a$$ down," Wack said.

Later on, Wack suggested Game's album is coming later this month.

Should Shady be worried?