Drake Makes Big Social Media Move Against Kanye West

Drake and Kanye West have been frenemies for a minute.

Now they just may be enemies.

Drake had unfollowed Kanye on Instagram after following his Calabasas' neighbor for five years.

We guess the whole Certified Lover Boy vs. Donda thing took its toll.

But you'd think Kanye would have been the one to unfollow.  We guess The Boy can't be a gracious winner.