Is it open season on Eminem?

Machine Gun Kelly went bar for bar with the Detroit legend last year and lived to tell about it.

Now Detroit upstart Tee Grizzley has some smoke for his local elder on his new track "No Talking".

"I run Detroit, n—-s talkin’ ’bout Eminem / Talking that sh*t, I kill you, him, and him," Grizzley spits.

It's far from the only hometown disrespect Shady's absorbed lately. Last week, MGK had a crowd in the Motor City chanting against Em. Last month, Detroit rapper Sada Baby said Eminem isn't top five in town and doesn't represent the D properly.

Does Em need to get out there and regulate?