It isn't 100 percent clear at this point, but there's a very good chance that 50 Cent responded to Nick Cannon calling him fat.

The Wild 'n Out host made the comment after 50's ex Vivica A. Fox said she'd be willing to get back with him.

"You can fantasize about Fif from 15 years ago. That’s a different Fif than this fat n*gga that’s walking around now," said Cannon on his Daily Cannon podcast recently. "He is fat! He look like he got a pack of hot dogs in the back of his neck. You looking at them pictures from Get Rich or Die Tryin’, now it’s get thick or die fryin.'"

50 posted an Instagram message on Monday, June 12, and again, it's very possible that he was responding to Cannon.

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A post shared by 50 Cent (@50cent)

"If your marketing campaign is say something about 50. Your not going to make it, have a nice day," wrote the rapper turned executive producer. 

 "It’s never luck. It’s always God," he also included in the actual post.

Should Cannon be worried?