Tupac's mom Afeni Shakur has passed away at age 69.

Afeni inspired the rap legend's song 'Dear Mama', and she guarded her son's legacy after his untimely death.

Police responded to Shakur’s Sausalito, California home last night, and then had Afeni transferred to the hospital. She was reported dead this morning of a suspected cardiac arrest.

Shakur was born Alice Faye Williams, but changed her name when she joined the Black Panthers. She had Tupac just months after being acquitted of conspiring to bomb New York City landmarks.

She will be credited as an executive producer for the upcoming Tupac biopic "All Eyez on Me,' which drops in November.

RIP, Afeni Shakur.

rest well Queen Afeni Shakur

— Efuru (@JheneAiko) May 3, 2016

R.I.P Afeni Shakur, thank you for your selfless contributions and blessings to the world. Love you forever unconditionally

— SKEPTA (@Skepta) May 3, 2016

RIP Afeni Shakur .....2 Pac finally has his mom back — Young Scrap (@youngscrap) May 3, 2016

Sad news about Pacs mom #AfeniShakur RIP Dear Mama learned a lot about being a women from watching you... pic.twitter.com/MMTxwYhrxI

— Pepa (@DaRealPepa) May 3, 2016

Dear Mama sounds different this morning... #AfeniShakur https://t.co/aPQFnqXNpu — J.U.S.T.I.C.E LEAGUE (@JusticeLeague) May 3, 2016

Ain't a women alive that can take my mommas place -2 Pac RIP Afeni Shakur pic.twitter.com/EQY1TV2uyk

— ITSBIZKIT (@itsbizkit) May 3, 2016

Rest in Power, Queen Afeni. Peace be unto you on your journey. Thank you for being with us while you were. — IG: TechImmortal (@ImmortalTech) May 3, 2016

Dear Mama reunites with her son. #blackpanther #activist #businesswoman #mother

A photo posted by Big Daddy Kane (@officialbigdaddykane) on May 3, 2016 at 7:43am PDT

Queen. rip #AfeniShakur. A photo posted by Questlove Gomez (@questlove) on May 3, 2016 at 7:51am PDT